Dog-DAT: a direct agglutination test using stabilized, freeze-dried antigen for the serodiagnosis of canine visceral leishmaniasis

We have evaluated the use of an improved direct agglutination test (DAT) based on stable, freeze-dried antigen for the detection of anti-Leishmania antibodies in canine serum samples. With a cut-off value of 1:640, the sensitivity of the DAT was shown to be 100% and the specificity of the test was 9...

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Veröffentlicht in:	FEMS immunology and medical microbiology 1996-12, Vol.16 (3/4), p.235-239
Hauptverfasser:	Oskam, L, Slappendel, R.J, Beijer, E.G.M, Kroon, N.C.M, Ingen, C.W. van, Ozensoy, S, Ozbel, Y, Terpstra, W.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Agglutination Agglutination Tests - methods animal health animal parasites and pests Animal protozoal diseases Animals Antibodies Antibodies, Protozoan - blood Antigens Antigens, Protozoan Biological and medical sciences Canine visceral leishmaniasis Direct agglutination test Dog Diseases - diagnosis Dogs Evaluation Studies as Topic Freeze Drying Infectious diseases Leishmania Leishmaniasis, Visceral - diagnosis Leishmaniasis, Visceral - epidemiology Leishmaniasis, Visceral - veterinary Medical sciences Netherlands - epidemiology Parasitic diseases Protozoa Protozoal diseases Sensitivity and Specificity Turkey - epidemiology Vector-borne diseases Visceral leishmaniasis
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Beschreibung
Zusammenfassung:	We have evaluated the use of an improved direct agglutination test (DAT) based on stable, freeze-dried antigen for the detection of anti-Leishmania antibodies in canine serum samples. With a cut-off value of 1:640, the sensitivity of the DAT was shown to be 100% and the specificity of the test was 98.8%.
ISSN:	0928-8244 1574-695X 2049-632X
DOI:	10.1111/j.1574-695X.1996.tb00141.x