Localization of glucocorticoid receptor in neuropeptide Y-containing neurons in the arcuate nucleus of the rat hypothalamus

Glucocorticoid receptor (GR) was localized immunohistochemically in nuclei of neurons in the arcuate nucleus of the rat hypothalamus. The double immunostaining method further revealed that about half of the GR-positive neurons in the arcuate nucleus were also immunoreactive for neuropeptide Y (NPY).

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Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience letters 1988-12, Vol.95 (1), p.13-18
Hauptverfasser:	Hisano, Setsuji, Kagotani, Yasuaki, Tsuruo, Yoshihiro, Daikoku, Shigeo, Chihara, Kazuo, Whitnall, Mark H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arcuate nucleus Arcuate Nucleus of Hypothalamus - cytology Arcuate Nucleus of Hypothalamus - metabolism Biological and medical sciences Corticotropin-releasing factor Fundamental and applied biological sciences. Psychology Glucocorticoid receptor Hormones and neuropeptides. Regulation Hypothalamus. Hypophysis. Epiphysis. Urophysis Immunohistochemistry Male Microscopy, Electron Neurons - metabolism Neuropeptide Y Neuropeptide Y - metabolism Paraventricular nucleus Rat Rats Rats, Inbred Strains Receptors, Glucocorticoid - metabolism Synapse Vertebrates: endocrinology
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Beschreibung
Zusammenfassung:	Glucocorticoid receptor (GR) was localized immunohistochemically in nuclei of neurons in the arcuate nucleus of the rat hypothalamus. The double immunostaining method further revealed that about half of the GR-positive neurons in the arcuate nucleus were also immunoreactive for neuropeptide Y (NPY).
ISSN:	0304-3940 1872-7972
DOI:	10.1016/0304-3940(88)90624-6