Primary extramedullary plasmacytoma of the head-neck area

A primary extramedullary plasmacytoma of the head and neck is a rare neoplasm with an incidence of 1%. The clinical features depend on localization. The clinical features, the method of diagnosis, and response to treatment of two cases with different localization were analysed. For diagnosis immunohistological and serological investigations are necessary. The method of treatment is determined by complete staging.