Cloning and Characterization of Two Novel Human cDNAs (NELL1 and NELL2) Encoding Proteins with Six EGF-like Repeats

From a human fetal-brain cDNA library we isolated two novel genes encoding peptides containing six EGF-like repeats. Both showed significant homologies with nel, a gene strongly expressed in neural tissues of chicken. The cDNAs, designated NELL1 (nel-like, type 1) and NELL2 (nel-like, type 2), conta...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 1996-12, Vol.38 (3), p.273-276
Hauptverfasser:	Watanabe, Takeshi K., Katagiri, Toyomasa, Suzuki, Mikio, Shimizu, Fumio, Fujiwara, Tsutomu, Kanemoto, Naohide, Nakamura, Yusuke, Hirai, Yoshikatsu, Maekawa, Hiroumi, Takahashi, Ei-ichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amino Acid Sequence Animals Base Sequence Biological and medical sciences Brain - embryology Brain - metabolism Chickens - genetics Chromosomes, Human, Pair 11 - genetics Chromosomes, Human, Pair 12 - genetics Cloning, Molecular DNA, Complementary - genetics Epidermal Growth Factor - chemistry Fetal Proteins - genetics Fetus - metabolism Fundamental and applied biological sciences. Psychology Genes. Genome Humans In Situ Hybridization, Fluorescence Kidney - embryology Kidney - metabolism Molecular and cellular biology Molecular genetics Molecular Sequence Data Nerve Tissue Proteins - genetics Open Reading Frames Sequence Homology, Amino Acid
Online-Zugang:	Volltext
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