Conditioned place preference produced by intra-hippocampal morphine

Conditioned place preference produced by intra-hippocampal morphine

Unilateral microinjections of morphine sulphate into the rat hippocampus were found to produce a conditioned place preference, whereas equi-volume saline injections into the same region in a separate control group were without effect. The results are discussed in terms of possible reward or habituat...

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Veröffentlicht in:Pharmacology, biochemistry and behavior biochemistry and behavior, 1988-07, Vol.30 (3), p.787-789
Hauptverfasser: Corrigall, William A., Linseman, Mary Ann
Format: Artikel
Sprache:eng
Schlagworte:
Analgesics
Animals
Biological and medical sciences
Conditioned place preference
Conditioning (Psychology) - drug effects
Habituation
Habituation, Psychophysiologic
Hippocampus
Hippocampus - drug effects
Hippocampus - physiology
Male
Medical sciences
Morphine
Morphine - pharmacology
Neuropharmacology
Opiate
Pharmacology. Drug treatments
Rats
Rats, Inbred Strains
Reference Values
Reinforcement
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Beschreibung
Zusammenfassung:Unilateral microinjections of morphine sulphate into the rat hippocampus were found to produce a conditioned place preference, whereas equi-volume saline injections into the same region in a separate control group were without effect. The results are discussed in terms of possible reward or habituation functions of the hippocampus.
ISSN:0091-3057
1873-5177
DOI:10.1016/0091-3057(88)90100-1