POST-TETANIC COUNT AND INTENSE NEUROMUSCULAR BLOCKADE WITH VECURONIUM IN CHILDREN

POST-TETANIC COUNT AND INTENSE NEUROMUSCULAR BLOCKADE WITH VECURONIUM IN CHILDREN

Sixty children undergoing surgery were allocated, according to weight, to three equal groups. Each child received a loading dose of vecuronium 80 μg kg−1 followed immediately by an infusion set initially at 1.4 μg kg−1 min−1. The subsequent intense neuromuscular blockade was assessed using the post-...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:British journal of anaesthesia : BJA 1988-11, Vol.61 (5), p.551-556
Hauptverfasser: RIDLEY, S.A., BRAUDE, N
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Anesthetics. Neuromuscular blocking agents
Biological and medical sciences
Child
Child, Preschool
Electric Stimulation
Humans
Infant
Infant, Newborn
Infusions, Intravenous
Medical sciences
Muscle Contraction - drug effects
Neuromuscular Junction - drug effects
Neuropharmacology
Pharmacology. Drug treatments
Time Factors
Vecuronium Bromide - administration & dosage
Vecuronium Bromide - pharmacology
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Sixty children undergoing surgery were allocated, according to weight, to three equal groups. Each child received a loading dose of vecuronium 80 μg kg−1 followed immediately by an infusion set initially at 1.4 μg kg−1 min−1. The subsequent intense neuromuscular blockade was assessed using the post-tetanic count (PTC). Maintaining the PTC between 5 and 15 ensured adequate paralysis which was antagonized easily 6–18 min after stopping the infusion. However, the duration of the initial intense block was unpredictable and the use of a peripheral nerve stimulator is advisable, particularly in smaller infants (
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/61.5.551