Papillary Squamous Cell Carcinoma of the Uterine Cervix: Report of a Case with HPV 16 DNA and Brief Review

Papillary squamous cell carcinoma (PSCC) of the uterine cervix is a rare variant of squamous cell carcinoma (SCC). It is characterized by a papillary architecture and markedly atypical epithelium. Invasion and metastasis have been reported. We report a case of PSCC in a 72-year-old woman who subsequ...

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Veröffentlicht in:	Gynecologic oncology 1996-12, Vol.63 (3), p.388-391
Hauptverfasser:	Ollayos, Curtis W., Lichy, Jack, Duncan, Beverly W., Ali, Izzat S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - virology DNA, Viral - isolation & purification Female Humans Papillomaviridae - isolation & purification Uterine Neoplasms - pathology Uterine Neoplasms - virology
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Zusammenfassung:	Papillary squamous cell carcinoma (PSCC) of the uterine cervix is a rare variant of squamous cell carcinoma (SCC). It is characterized by a papillary architecture and markedly atypical epithelium. Invasion and metastasis have been reported. We report a case of PSCC in a 72-year-old woman who subsequently tested positive for HPV 16. To our knowledge, this is the first report of HPV typing in a case of PSCC. Our finding of a high-risk HPV type in PSCC may help explain why PSCC has been reported to have a clinical course similar to that of nonpapillary SCC.
ISSN:	0090-8258 1095-6859
DOI:	10.1006/gyno.1996.0341