Immunity in filariasis: perspectives for vaccine development

The authors' aim is to review the immunobiology of filariae that infect humans, in both natural and experimental infections, and the available strategies for the identification of host-protective antigens. With this information as a background, they analyze the prospects for vaccine development...

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Veröffentlicht in:	Annual review of microbiology 1988-01, Vol.42 (1), p.685-716
Hauptverfasser:	PHILIPP, M, DAVIS, T. B, STOREY, N, CARLOW, C. K. S
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Helminth - analysis Antigens, Surface - analysis Biological and medical sciences Brugia - immunology Disease Models, Animal Diseases caused by nematodes Filariasis - immunology Filarioidea - immunology Helminthic diseases Humans Infectious diseases Medical sciences Microfilariae - immunology Onchocerca - immunology Parasitic diseases
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Beschreibung
Zusammenfassung:	The authors' aim is to review the immunobiology of filariae that infect humans, in both natural and experimental infections, and the available strategies for the identification of host-protective antigens. With this information as a background, they analyze the prospects for vaccine development.
ISSN:	0066-4227 1545-3251
DOI:	10.1146/annurev.mi.42.100188.003345