Acute encephalitis with intrathecal synthesis of measles antibodies

There are three well-defined inflammatory diseases which are characterized by synthesis of measles antibodies de novo within the central nervous system (CNS): subacute sclerosing panencephalitis (SSPE), a chronic progressive disease of children and young adults with an invariable fatal outcome; acute measles encephalitis, a monophasic disease of childhood that follows systemic measles infection; and multiple sclerosis (MS).