Serum and urinary nitrate levels in liver cirrhosis: endotoxemia, renal function and hyperdynamic circulation

Serum and urinary nitrate levels in liver cirrhosis: endotoxemia, renal function and hyperdynamic circulation

Background/Aims: The relationship between nitric oxide production, endotoxemia, renal function and hyperdynamic circulatory syndrome has not been yet investigated in patients with cirrhosis. Methods: Serum and urine nitrate, endotoxemia and cardiac index were measured in 59 patients with cirrhosis....

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Veröffentlicht in:Journal of hepatology 1996-11, Vol.25 (5), p.707-714
Hauptverfasser: Campillo, Bernard, Bories, Phuong Nhi, Benvenuti, Christophe, Dupeyron, Catherine
Format: Artikel
Sprache:eng
Schlagworte:
Analysis of Variance
Ascites
Biological and medical sciences
Cardiac output
Cardiac Output, High - physiopathology
Case-Control Studies
Cirrhosis
Echocardiography, Doppler
Endotoxemia
Endotoxemia - blood
Endotoxemia - metabolism
Endotoxemia - urine
Female
Gastroenterology. Liver. Pancreas. Abdomen
Hemodynamics - physiology
Humans
Inflammatory proteins
Kidney - physiopathology
Liver Cirrhosis - blood
Liver Cirrhosis - metabolism
Liver Cirrhosis - urine
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Middle Aged
Nitrates - blood
Nitrates - metabolism
Nitrates - urine
Nitric Oxide - biosynthesis
Other diseases. Semiology
Regional Blood Flow
Renal function
Serum and urine nitrate
Syndrome
Vasodilation - physiology
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Zusammenfassung:Background/Aims: The relationship between nitric oxide production, endotoxemia, renal function and hyperdynamic circulatory syndrome has not been yet investigated in patients with cirrhosis. Methods: Serum and urine nitrate, endotoxemia and cardiac index were measured in 59 patients with cirrhosis. Results: Patients with a tense ascites had higher serum nitrate levels than health control subjects (39±7 vs 19±4 μmol/l, p
ISSN:0168-8278
1600-0641
DOI:10.1016/S0168-8278(96)80242-X