Chronic urticaria: review of nonsedating H1 antihistamines in treatment

Antihistamines are the drugs of choice in the symptomatic relief of chronic urticaria; however, the usefulness of classic antihistamines has been limited by side effects, especially daytime sedation. In the 1980s a new class of antihistamines has been developed that maintains effectiveness and produ...

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Veröffentlicht in:	Journal of the American Academy of Dermatology 1988-11, Vol.19 (5), p.842-849
1. Verfasser:	MONROE, E. W
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Chronic Disease Histamine and antagonists. Allergy Histamine H1 Antagonists - administration & dosage Histamine H1 Antagonists - adverse effects Histamine H1 Antagonists - therapeutic use Humans Medical sciences Pharmacology. Drug treatments Sleep Stages - drug effects Urticaria - drug therapy
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Beschreibung
Zusammenfassung:	Antihistamines are the drugs of choice in the symptomatic relief of chronic urticaria; however, the usefulness of classic antihistamines has been limited by side effects, especially daytime sedation. In the 1980s a new class of antihistamines has been developed that maintains effectiveness and produces less sedation. This review analyzes each of the new nonsedating antihistamines and evaluates its clinical efficacy, safety, and convenience in the treatment of chronic urticaria.
ISSN:	0190-9622 1097-6787
DOI:	10.1016/S0190-9622(88)70243-1