First demonstration of recombination between the gene for Norrie disease and probe L1.28

Norrie disease is an X‐linked trait thought ot be tightly linked to the anonymous probe L1.28. Here we repost the first recombinational event amony 24 informative meioses. This indicates there is a 4% (95% C.L. 0.1%–21%) error rate introduced by meiotic crossovers in carrier or prenatal diagnosis based on linkage between Norrie disease and L1.28.