Relations between Radiographic Trabecular Pattern and Biomechanical Characteristics of Human Vertebrae

Purpose: Relations between the radiographic trabecular pattern and the biomechanical characteristics of bone were studied. Material and Methods: The material comprised L2 and L3 vertebral bodies of 14 individuals (aged 22−76 years; 6 women and 8 men). Compressive strength and ash density of the complete L2 vertebral body were determined. Of the L3 vertebral body, ash density and compressive strength in both horizontal and vertical directions were measured on cylinders of merely trabecular bone. Radiographs were taken of a midsagittal slice of L3 vertebrae. They were digitized to measure trabecular bone geometry and orientation. The procedure was repeated several times to obtain reliable measures. Results: The radiographic trabecular pattern was significantly related to compressive strength, ash density and age. One of the radiographic geometric features in particular seems to offer information concerning the structural integrity of the trabecular architecture. Conclusion: Analysis of the radiographic trabecular pattern appears to be a promising technique for prediction of trabecular bone strength.