Comparison of Whole Blood and Plasma Morphine

Comparison of Whole Blood and Plasma Morphine

Thirty paired samples of plasma and whole hemolyzed blood were obtained from patients undergoing surgery. Morphine concentrations were measured with the DPC serum morphine kit without prior treatment. In a regression analysis, the equation to the regression line was blood = 1.02 plasma + 1.0 ng/mL,...

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Veröffentlicht in:Journal of analytical toxicology 1988-07, Vol.12 (4), p.234-235
Hauptverfasser: Hand, C.W., Moore, R.A., Sear, J.W.
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Drug addictions
Humans
Intraoperative Period
Mathematical models
Medical sciences
Morphine
Morphine - blood
Radioimmunoassay
Reagent Kits, Diagnostic
Regression analysis
Surgery
Toxicology
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Zusammenfassung:Thirty paired samples of plasma and whole hemolyzed blood were obtained from patients undergoing surgery. Morphine concentrations were measured with the DPC serum morphine kit without prior treatment. In a regression analysis, the equation to the regression line was blood = 1.02 plasma + 1.0 ng/mL, and the correlation coefficient was 0.994. Radioimmunoassay screening of postmortem blood samples can be performed without prior sample treatment.
ISSN:0146-4760
1945-2403
DOI:10.1093/jat/12.4.234