Immunohistochemical analysis of distribution of estrogen receptors and progesterone receptors in the postmenopausal endometrium

Immunohistochemical analysis of distribution of estrogen receptors and progesterone receptors in the postmenopausal endometrium

Objective. To examine the expression of sex steroid receptors (ER: estrogen receptor; PR: progesterone receptor) in the postmenopausal endometrium (PMEM) and the relationship to clinical data for studying its characters. Methods. The immunohistochemical reactivity of the PMEM was studied using monoc...

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Veröffentlicht in:Acta obstetricia et gynecologica Scandinavica 1996-08, Vol.75 (8), p.702-706
Hauptverfasser: Koshiyama, Masafumi, Yoshida, Masumi, Takemura, Maki, Yura, Yasuichirou, Matsushita, Katsuko, Hayashi, Michiharu, Tauchi, Kunihiko, Konishi, Ikuo, Mori, Takahide
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
aging
Aging - physiology
Antibodies, Monoclonal
Biological and medical sciences
endometrial thickness
Endometrium - anatomy & histology
Endometrium - chemistry
estrogen receptor
Female
Fundamental and applied biological sciences. Psychology
Hormone metabolism and regulation
Humans
Immunohistochemistry
Mammalian female genital system
Middle Aged
postmenopausal endometrium
Postmenopause - metabolism
progesterone receptor
Receptors, Estrogen - analysis
Receptors, Progesterone - analysis
Vertebrates: reproduction
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Zusammenfassung:Objective. To examine the expression of sex steroid receptors (ER: estrogen receptor; PR: progesterone receptor) in the postmenopausal endometrium (PMEM) and the relationship to clinical data for studying its characters. Methods. The immunohistochemical reactivity of the PMEM was studied using monoclonal antibodies against ER and PR, in 33 postmenopausal patients. Results. The endometrium was thicker in patients who were postmenopausal for 1 to 10 years (1.48±1.31mm) than in patients who were postmenopausal for more than 10 years (0.79 ± 0.37mm) (p
ISSN:0001-6349
1600-0412
DOI:10.3109/00016349609065730