Polyradiculoneuropathy with Cerebrospinal Fluid Albuminocytological Dissociation Due to Neurobrucellosis

Brucellosis is an infection caused by gram-negative microorganisms of the genus Brucella that are transmitted to humans by domesticated animals. Involvement of the nervous system occurs in 5%-10% of cases of systemic brucellosis, and clinical manifestations may imitate several neurological disorders...

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Veröffentlicht in:Clinical infectious diseases 1996-10, Vol.23 (4), p.833-834
Hauptverfasser: Oliveri, Rosario Luciano, Matera, Giovanni, Focà, Alfredo, Zappia, Mario, Aguglia, Umberto, Quattrone, Aldo
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Sprache:eng
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Zusammenfassung:Brucellosis is an infection caused by gram-negative microorganisms of the genus Brucella that are transmitted to humans by domesticated animals. Involvement of the nervous system occurs in 5%-10% of cases of systemic brucellosis, and clinical manifestations may imitate several neurological disorders. Criteria for definite diagnosis of neurobrucellosis are (1) abnormal CSF, with an increased protein level and lymphocytic pleocytosis; (2) positive Brucella agglutination tests and high titers of antibody in the blood and CSF; and (3) a clinical response to chemotherapy. We report a case of polyradiculoneuropathy caused by neurobrucellosis in a man whose CSF and hematological findings were misleading.
ISSN:1058-4838
1537-6591
DOI:10.1093/clinids/23.4.833