Diagnostic Accuracy of Outpatient Endocervical Curettage Using Conventional and Vabra Curettage of the Cervix

With the object of examining the diagnostic accuracy of and pain reaction to endo-cervical curettage (ECC) either by using a new instrument, Vabra® mc cervix, or with a conventional 3 mm metal curette, 298 patients with histologically verified cervical intra-epithelial neoplasia (CIN) or cytological suspicion have been involved in a consecutive prospective randomized trial. One hundred and forty-eight patients underwent curettage with the Vabra instrument (vabrasiol followed by conventional curettage; 150 underwent the same procedure, but in reverse order. In 114 patients, CIN was ascertained in one or both trials. Vabra® mc cervix found normal histology in 23 of these patients (20%), whereas conventional curettage showed normal histology in 58 patients (51%). Quantitatively, Vabra® mc cervix extracted significantly more tissue material than did conventional curettage. The pain intensity when using of Vabra® mc cervix was less servere. The present study showed diagnostic accuracy of Vabra® me cervix to be 80% (95% confidence limits: 63.38-80.73). compared with 49% (95% confidence limits: 35.17-54.35) when using conventional curettage.