Circumscribed lytic lesions of the thalassaemic skull

Circumscribed lytic lesions of the thalassaemic skull

Solitary or multiple circumscribed osteolytic areas are described in seven patients, selected from 250 patients with homozygous beta-thalassaemia (Cooley's anaemia). On X-ray examinations, these areas appear as purely osteolytic lesions with well-defined margins not associated with sclerosis. T...

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Veröffentlicht in:Skeletal radiology 1988-07, Vol.17 (5), p.344-347
Hauptverfasser: ORZINCOLO, C, CASTALDI, G, BARIANI, L, FRANCESCHINI, F, CORCIONE, S, SCUTELLARI, P. N
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Anemias. Hemoglobinopathies
Biological and medical sciences
Child
Diseases of red blood cells
Female
Hematologic and hematopoietic diseases
Humans
Male
Medical sciences
Osteolysis - diagnostic imaging
Osteolysis - etiology
Radiography
Skull - diagnostic imaging
Thalassemia - complications
Thalassemia - diagnostic imaging
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Zusammenfassung:Solitary or multiple circumscribed osteolytic areas are described in seven patients, selected from 250 patients with homozygous beta-thalassaemia (Cooley's anaemia). On X-ray examinations, these areas appear as purely osteolytic lesions with well-defined margins not associated with sclerosis. The possible mechanisms are discussed.
ISSN:0364-2348
1432-2161
DOI:10.1007/BF00367180