Mapping of Unconventional Myosins in Mouse and Human

Myosins are molecular motors that move along filamentous actin. Seven classes of myosin are expressed in vertebrates: conventional myosin, or myosin-II, as well as the 6 unconventional myosin classes -I, -V, -VI, -VII, -IX, and -X. We have mapped in mouse 22 probes encompassing all known unconventio...

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Veröffentlicht in:	Genomics (San Diego, Calif.) Calif.), 1996-09, Vol.36 (3), p.431-439
Hauptverfasser:	Hasson, Tama, Skowron, Joseph F., Gilbert, Debra J., Avraham, Karen B., Perry, William L., Bement, William M., Anderson, Blake L., Sherr, Elliott H., Chen, Zheng-Yi, Greene, Lloyd A., Ward, David C., Corey, David P., Mooseker, Mark S., Copeland, Neal G., Jenkins, Nancy A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Chromosome Mapping Classical genetics, quantitative genetics, hybrids Female Fundamental and applied biological sciences. Psychology Genetics of eukaryotes. Biological and molecular evolution Human Humans In Situ Hybridization, Fluorescence Male Mice Mice, Inbred C57BL Molecular Sequence Data Myosins - genetics
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Zusammenfassung:	Myosins are molecular motors that move along filamentous actin. Seven classes of myosin are expressed in vertebrates: conventional myosin, or myosin-II, as well as the 6 unconventional myosin classes -I, -V, -VI, -VII, -IX, and -X. We have mapped in mouse 22 probes encompassing all known unconventional myosins and, as a result, have identified 16 potential unconventional myosin genes. These genes include 7 myosins-I, 2 myosins-V, 1 myosin-VI, 3 myosins-VII, 2 myosins-IX, and 1 myosin-X. The map location of 5 of these genes was identified in human chromosomes by fluorescencein situhybridization.
ISSN:	0888-7543 1089-8646
DOI:	10.1006/geno.1996.0488