Persistent tubal ectopic gestation: patterns of circulating β-human chorionic gonadotropin and progesterone, and management options

To aid in the clinical decision making involved with persistent ectopic gestation, a total of 329 operative procedures for tubal gestation were reviewed. Six of 114 (5.3%) cases treated conservatively had persistent trophoblastic activity. The decline in serum β-human chorionic gonadotropin (hCG) an...

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Veröffentlicht in:	Fertility and sterility 1988-10, Vol.50 (4), p.584-588
Hauptverfasser:	Vermesh, Michael, Silva, Paul D., Sauer, Mark V., Vargyas, Joyce M., Lobo, Rogerio A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Chorionic Gonadotropin - blood Chorionic Gonadotropin, beta Subunit, Human Diseases of mother, fetus and pregnancy Female Gynecology. Andrology. Obstetrics Humans Medical sciences Peptide Fragments - blood Pregnancy Pregnancy, Ectopic - blood Pregnancy, Ectopic - epidemiology Pregnancy, Ectopic - therapy Pregnancy. Fetus. Placenta Progesterone - blood Recurrence
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Zusammenfassung:	To aid in the clinical decision making involved with persistent ectopic gestation, a total of 329 operative procedures for tubal gestation were reviewed. Six of 114 (5.3%) cases treated conservatively had persistent trophoblastic activity. The decline in serum β-human chorionic gonadotropin (hCG) and progesterone (P) at 3 and 6days postoperatively was similar in the “persistent ectopic” and the “resolved ectopic” groups. However, beyond day 6 both β-hCG percentage of baseline and P level were significantly higher in the “persistent ectopic” (>22.6±6.6%, >3.4±0.7ng/ml, respectively) than the “resolved ectopic” group (
ISSN:	0015-0282 1556-5653
DOI:	10.1016/S0015-0282(16)60187-5