Lewis Lung Carcinoma Cells Enhance the Synthesis of C3 and are Opsonized by C3 Secreted from Murine Macrophages

Lewis Lung Carcinoma Cells Enhance the Synthesis of C3 and are Opsonized by C3 Secreted from Murine Macrophages

We investigated the effect of Lewis Lung carcinoma cells on the production of C3 by murine macrophages and examined the capacity of secreted C3 to op On Western blots of concentrated macrophage supernatants, there was partial cleavage of secreted C3 which was, however, not more pronounced in the cas...

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Veröffentlicht in:Immunobiology (1979) 1988-07, Vol.177 (3), p.233-244
Hauptverfasser: Lipari, Marcella, Di Renzo, Livia, Zicari, Alessandra, Schulz, Thomas F., Magliocca, Antonello, Mardente, Stefania, Dierich, Manfred P., Pontieri, Giuseppe M.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biological and medical sciences
Complement
Complement C3 - biosynthesis
Female
Fundamental and applied biological sciences. Psychology
Fundamental immunology
In Vitro Techniques
Lung Neoplasms - immunology
Macrophages - immunology
Male
Mice
Mice, Inbred C57BL
Molecular immunology
Opsonin Proteins
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Zusammenfassung:We investigated the effect of Lewis Lung carcinoma cells on the production of C3 by murine macrophages and examined the capacity of secreted C3 to op On Western blots of concentrated macrophage supernatants, there was partial cleavage of secreted C3 which was, however, not more pronounced in the case of C3
ISSN:0171-2985
1878-3279
DOI:10.1016/S0171-2985(88)80043-3