G protein multiplicity in eukaryotic signal transduction systems

G proteins comprise a specific family of guanine nucleotide binding regulatory proteins that serve as intermediaries in a variety of transmembrane signaling processes in eukaryotic cells. They are located on the cytoplasmic surface of membranes, where they physically couple ligand-bound receptors to...

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Veröffentlicht in:	Biochemistry (Easton) 1988-07, Vol.27 (14), p.4957-4965
Hauptverfasser:	Lochrie, Michael A, Simon, Melvin I
Format:	Artikel
Sprache:	eng
Schlagworte:	Acylation Adenosine Diphosphate Ribose - metabolism Amino Acid Sequence Analytical, structural and metabolic biochemistry Animals Binding and carrier proteins Biological and medical sciences Cattle DNA - analysis Fundamental and applied biological sciences. Psychology GTP-Binding Proteins - analysis GTP-Binding Proteins - genetics GTP-Binding Proteins - physiology guanine nucleotide-binding proteins Humans Molecular Sequence Data Phosphorylation Proteins Rats reviews
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Beschreibung
Zusammenfassung:	G proteins comprise a specific family of guanine nucleotide binding regulatory proteins that serve as intermediaries in a variety of transmembrane signaling processes in eukaryotic cells. They are located on the cytoplasmic surface of membranes, where they physically couple ligand-bound receptors to the regulation of effector proteins which produce changes in intracellular metabolism.
ISSN:	0006-2960 1520-4995
DOI:	10.1021/bi00414a001