HLA antigens in schizophrenia and mood disorders

The frequencies of HLA antigens were examined in a sample of 75 patients with schizophrenia and 35 patients with mood disorders. We compared the data obtained from this population with data obtained in another study with 3731 healthy subjects. Statistically significant increases were observed in the...

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Veröffentlicht in:	Biological psychiatry (1969) 1996-05, Vol.39 (10), p.891-895
Hauptverfasser:	Erkan Özcan, M., Ta§kin, Rana, Banoğlu, Ramiz, Babacan, Mete, Tuncer, Erdal
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Autoimmunity Biological and medical sciences depression Female HLA HLA Antigens - immunology Humans Male mania Medical sciences Mood Disorders - immunology paranoid Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Schizophrenia Schizophrenia, Paranoid - immunology undifferentiated
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Beschreibung
Zusammenfassung:	The frequencies of HLA antigens were examined in a sample of 75 patients with schizophrenia and 35 patients with mood disorders. We compared the data obtained from this population with data obtained in another study with 3731 healthy subjects. Statistically significant increases were observed in the frequencies of HLA A10, A11, and A29 and a statistically significant decrease was observed in the frequency of HLA A2 in patients with schizophrenia. The increased frequency in HLA B16 in patients with mood disorders was also statistically significant.
ISSN:	0006-3223 1873-2402
DOI:	10.1016/0006-3223(95)00223-5