Use of standardized SCID-hu Thy/Liv mouse model for preclinical efficacy testing of anti-human immunodeficiency virus type 1 compounds

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Veröffentlicht in:	Antimicrobial Agents and Chemotherapy 1996-03, Vol.40 (3), p.755-762
Hauptverfasser:	Rabin, L, Hincenbergs, M, Moreno, M B, Warren, S, Linquist, V, Datema, R, Charpiot, B, Seifert, J, Kaneshima, H, McCune, J M
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Animals Antiviral Agents Antiviral Agents - pharmacology Didanosine - therapeutic use DNA, Viral - analysis Enzyme-Linked Immunosorbent Assay Fetal Tissue Transplantation Flow Cytometry HIV Core Protein p24 - analysis HIV Infections HIV Infections - drug therapy HIV Infections - immunology HIV Infections - virology HIV-1 HIV-1 - isolation & purification human immunodeficiency virus 1 Humans Liver Transplantation - physiology Lymphocyte Count - drug effects Mice Mice, SCID Mice, SCID - virology Neutrophils - drug effects Neutrophils - immunology Neutrophils - microbiology Nevirapine Polymerase Chain Reaction Pyridines - pharmacokinetics Pyridines - therapeutic use Rats Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S T-Lymphocytes - immunology Thymus Gland - transplantation Transplantation, Heterologous Zidovudine - therapeutic use
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Zusammenfassung:	Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC
ISSN:	0066-4804 1098-6596
DOI:	10.1128/AAC.40.3.755