NEW ANTIBIOTICS SF2315A AND B PRODUCED BY AN EXCELLOSPORA SP: I. TAXONOMY OF THE STRAIN, ISOLATION AND CHARACTERIZATION OF ANTIBIOTICS

Two new antibiotics SF2315A and B have been isolated from culture filtrate of an actinomycete strain, Excellospora viridilutea SF2315. They are weakly active against Gram-positive bacteria and inhibited reverse transcriptase of avian myeloblastosis virus. Empirical molecular formula of antibiotics S...

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Veröffentlicht in:	Journal of antibiotics 1988/07/25, Vol.41(7), pp.835-842
Hauptverfasser:	SASAKI, TORU, YOSHIDA, JUNKO, ITOH, MITSUGU, GOMI, SHUICHI, SHOMURA, TAKASHI, SEZAKI, MASAJI
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinomycetales - classification Actinomycetales - metabolism Animals Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Antibacterial agents Antibiotics Antibiotics. Antiinfectious agents. Antiparasitic agents Benz(a)Anthracenes - isolation & purification Benz(a)Anthracenes - pharmacology Biological and medical sciences Biotechnology Chemical Phenomena Chemistry Fermentation Fundamental and applied biological sciences. Psychology Health. Pharmaceutical industry Industrial applications and implications. Economical aspects Medical sciences Mice Pharmacology. Drug treatments Production of active biomolecules
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Zusammenfassung:	Two new antibiotics SF2315A and B have been isolated from culture filtrate of an actinomycete strain, Excellospora viridilutea SF2315. They are weakly active against Gram-positive bacteria and inhibited reverse transcriptase of avian myeloblastosis virus. Empirical molecular formula of antibiotics SF2315A and B were determined to be C19H16O5 and C19H20O6, respectively.
ISSN:	0021-8820 1881-1469
DOI:	10.7164/antibiotics.41.835