Maternal Arterial Desaturation With 15-Methyl Prostaglandin F2 Alpha for Uterine Atony

Over a six-month period, five women with severe uterine atony and postpartum hemorrhage developed marked maternal arterial oxygen desaturation within five to ten minutes of the administration of 15-methyl prostaglandin F2α. The average fall from baseline was 10.4 ± 5.4%, to a mean arterial oxygen sa...

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Veröffentlicht in:	Obstetrics and gynecology (New York. 1953) 1988-09, Vol.72 (3), p.367-370
Hauptverfasser:	HANKINS, GARY D. V, BERRYMAN, GREGORY K, SCOTT, RICHARD T, HOOD, DAVID
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood Gas Analysis Carboprost - adverse effects Carboprost - therapeutic use Delivery. Postpartum. Lactation Disorders Female Gynecology. Andrology. Obstetrics Humans Medical sciences Oximetry Oxygen - blood Postpartum Hemorrhage - blood Pregnancy Prostaglandins F, Synthetic - adverse effects Time Factors Uterine Inertia - blood Uterine Inertia - complications Uterine Inertia - drug therapy
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Zusammenfassung:	Over a six-month period, five women with severe uterine atony and postpartum hemorrhage developed marked maternal arterial oxygen desaturation within five to ten minutes of the administration of 15-methyl prostaglandin F2α. The average fall from baseline was 10.4 ± 5.4%, to a mean arterial oxygen saturation of 88.8 ± 5.45%. The desaturation was accompanied by acute increases, averaging 20.7 ± 5.9%, in the intrapulmonary shunt.
ISSN:	0029-7844 1873-233X