Application to Rat Lung of the Extended Rorschach–Hazlewood Model of Spin–Lattice Relaxation

Application to Rat Lung of the Extended Rorschach–Hazlewood Model of Spin–Lattice Relaxation

The spin–lattice relaxation timeT1was measured in excised degassed (airless) rat lungs over the frequency range 6.7 to 80.5 MHz. The observed frequency dependence was fitted successfully to the water–biopolymer cross-relaxation theory proposed by H. E. Rorschach and C. F. Hazlewood (RH) [J. Magn. Re...

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Veröffentlicht in:Journal of magnetic resonance. Series B 1996-02, Vol.110 (2), p.136-137
Hauptverfasser: Hackmann, Andreas, Ailion, David C., Ganesan, Krishnamurthy, Goodrich, K.Craig, Chen, Songhua, Laicher, Gernot, Cutillo, Antonio G.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Female
Lung - metabolism
Macromolecular Substances
Magnetic Resonance Spectroscopy
Models, Theoretical
Oxygen Consumption
Pulmonary Atelectasis - metabolism
Rats
Rats, Sprague-Dawley
Water
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Zusammenfassung:The spin–lattice relaxation timeT1was measured in excised degassed (airless) rat lungs over the frequency range 6.7 to 80.5 MHz. The observed frequency dependence was fitted successfully to the water–biopolymer cross-relaxation theory proposed by H. E. Rorschach and C. F. Hazlewood (RH) [J. Magn. Reson.70,79 (1986)]. The rotating frame spin–lattice relaxation timeT1ρwas also measured in rat lung fragments over the frequency range 0.56 to 5.6 kHz, and the observed frequency dependence was explained with an extension of the RH model. The agreement between the theory and the experimental data in both cases is good.
ISSN:1064-1866
1096-0872
DOI:10.1006/jmrb.1996.0022