Minimal change glomerulonephropathy and interstitial infiltration with mycosis fungoides

The nephrotic syndrome developed in a patient with mycosis fungoides shortly after systemic involvement by his tumor occurred. Renal biopsy examination revealed atypical lymphocytic interstitial infiltration and changes consistent with minimal change glomerulonephropathy. The patient's proteinu...

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Veröffentlicht in:The American journal of medicine 1988-04, Vol.84 (4), p.756-759
Hauptverfasser: Allon, Michael, Campbell, Wallace G., Nasr, Sherif A., Bourke, Edmund, Stoute, Jose, Guntupalli, Jayarama
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Sprache:eng
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Zusammenfassung:The nephrotic syndrome developed in a patient with mycosis fungoides shortly after systemic involvement by his tumor occurred. Renal biopsy examination revealed atypical lymphocytic interstitial infiltration and changes consistent with minimal change glomerulonephropathy. The patient's proteinuria decreased following steroid therapy. This is the first report of an association between minimal change glomerulonephropathy and a proven T-cell malignant lymphoma. The implications are discussed with reference to the literature.
ISSN:0002-9343
1555-7162
DOI:10.1016/0002-9343(88)90115-5