Antibacterial activity of the phenolic acids fractions of Scrophularia frutescens and Scrophularia sambucifolia

Antibacterial activity of the phenolic acids fractions of Scrophularia frutescens and Scrophularia sambucifolia

The phenolic fractions of aerial part of Scrophularia frutescens and S. sambucifolia (Scrophulariaceae) showed a potent antibacterial activity. Ferulic, isovanillic, p-hydroxycinnamic, p-hydroxybenzoic, syringic, caffeic, gentisic and protocatechuic acids were isolated from S. frutescens and ferulic...

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Veröffentlicht in:Journal of ethnopharmacology 1996-07, Vol.53 (1), p.11-14
Hauptverfasser: FERNANDEZ, M. A, GARCIA, M. D, SAENZ, M. T
Format: Artikel
Sprache:eng
Schlagworte:
Anti-Bacterial Agents - isolation & purification
Anti-Bacterial Agents - metabolism
Anti-Bacterial Agents - pharmacology
Antibacterial
Bacillus - drug effects
Bacillus - metabolism
Biological and medical sciences
Caffeic Acids - isolation & purification
Caffeic Acids - metabolism
Caffeic Acids - pharmacology
Chemical Fractionation
Coumaric Acids - isolation & purification
Coumaric Acids - metabolism
Coumaric Acids - pharmacology
Escherichia coli - drug effects
Escherichia coli - metabolism
Free Radical Scavengers - isolation & purification
Free Radical Scavengers - metabolism
Free Radical Scavengers - pharmacology
Gallic Acid - analogs & derivatives
Gallic Acid - isolation & purification
Gallic Acid - metabolism
Gallic Acid - pharmacology
General pharmacology
Gentisates
Hydroxybenzoates - isolation & purification
Hydroxybenzoates - metabolism
Hydroxybenzoates - pharmacology
Medical sciences
Moraxella - drug effects
Moraxella - metabolism
Parabens - isolation & purification
Parabens - metabolism
Parabens - pharmacology
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phenolic
Plant Extracts - metabolism
Plant Extracts - pharmacology
Plants, Medicinal
Propionates
S. sambucifolia
Salmonella typhimurium - drug effects
Salmonella typhimurium - metabolism
Scrophularia frutescens
Serratia marcescens - drug effects
Serratia marcescens - metabolism
Structure-Activity Relationship
Vanillic Acid - analogs & derivatives
Vanillic Acid - isolation & purification
Vanillic Acid - metabolism
Vanillic Acid - pharmacology
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Zusammenfassung:The phenolic fractions of aerial part of Scrophularia frutescens and S. sambucifolia (Scrophulariaceae) showed a potent antibacterial activity. Ferulic, isovanillic, p-hydroxycinnamic, p-hydroxybenzoic, syringic, caffeic, gentisic and protocatechuic acids were isolated from S. frutescens and ferulic, p-coumaric, vanillic, p-hydroxibenzoic and syringic acids were isolated from S. sambucifolia. Since phenolic acids have been shown in the literature to exert an antibacterial effect, the presence of these compounds in the two plants explains their antibacterial activity.
ISSN:0378-8741
1872-7573
DOI:10.1016/0378-8741(96)01419-5