Mechanisms of Hepatocyte Growth Factor Stimulation of Keratinocyte Metalloproteinase Production

Matrix metalloproteinases participate in normal physiologic processes; however, their overproduction has been associated with connective tissue destruction in a variety of pathological states. Migrating basal keratinocytes transiently express collagenase-1 during normal cutaneous reepithelialization...

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Veröffentlicht in:	The Journal of biological chemistry 1996-10, Vol.271 (40), p.24576-24582
Hauptverfasser:	Dunsmore, S E, Rubin, J S, Kovacs, S O, Chedid, M, Parks, W C, Welgus, H G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Cells, Cultured Collagenases - biosynthesis Heparin - pharmacology Hepatocyte Growth Factor - antagonists & inhibitors Hepatocyte Growth Factor - pharmacology Humans Keratinocytes - drug effects Keratinocytes - enzymology Matrix Metalloproteinase 3 - biosynthesis Protein Kinase C - metabolism Protein-Tyrosine Kinases - metabolism
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