Structural classification of proteins: new superfamilies

The structural classification of proteins reveals that it is already more likely to find that a new protein structure has similarity to another structure than to find that it has a new fold. Reviewed here are those new superfamilies that include proteins of general interest: Sonic hedgehog, macropha...

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Veröffentlicht in:	Current opinion in structural biology 1996-06, Vol.6 (3), p.386-394
1. Verfasser:	Murzin, Alexey G
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Alcohol Dehydrogenase - chemistry Carrier Proteins - chemistry Chaperonin 10 - chemistry Flavin-Adenine Dinucleotide - metabolism Hedgehog Proteins Humans Ligases - chemistry Ligases - metabolism Macrophage Migration-Inhibitory Factors - chemistry Models, Molecular Nuclear Proteins - chemistry Nucleocytoplasmic Transport Proteins Protein Conformation Proteins - chemistry Proteins - classification RNA, Double-Stranded - chemistry Trans-Activators
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Beschreibung
Zusammenfassung:	The structural classification of proteins reveals that it is already more likely to find that a new protein structure has similarity to another structure than to find that it has a new fold. Reviewed here are those new superfamilies that include proteins of general interest: Sonic hedgehog, macrophage migration inhibitory factor, nuclear transport factor-2, double stranded RNA binding domain, GroES, the proteasome, new ATP-hydrolyzing ligases and flavoproteins.
ISSN:	0959-440X 1879-033X
DOI:	10.1016/S0959-440X(96)80059-5