Nimodipine in Acute Ischemic Stroke

Nimodipine in Acute Ischemic Stroke

To the Editor: Gelmers et al. (Jan. 28 issue) 1 have reported beneficial effects of early treatment with nimodipine in cases of acute ischemic stroke. We conducted a similar double-blind study with inclusion and exclusion criteria almost identical to those used by Gelmers et al. The diagnosis of acu...

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Veröffentlicht in:The New England journal of medicine 1988-07, Vol.319 (4), p.249-251
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Sprache:eng
Schlagworte:
Acute Disease
Brain Ischemia - drug therapy
Clinical Trials as Topic
Humans
Nimodipine - therapeutic use
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description To the Editor: Gelmers et al. (Jan. 28 issue) 1 have reported beneficial effects of early treatment with nimodipine in cases of acute ischemic stroke. We conducted a similar double-blind study with inclusion and exclusion criteria almost identical to those used by Gelmers et al. The diagnosis of acute stroke was confirmed by a complete neurologic workup that included a CT scan. Patients were randomly assigned to receive either oral nimodipine (30 mg four times a day) or matched placebo tablets for 28 days. The study medication was always started within 48 hours after the onset of symptoms. No concomitant standardized . . .
doi_str_mv 10.1056/NEJM198807283190415
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subjects Acute Disease
Brain Ischemia - drug therapy
Clinical Trials as Topic
Humans
Nimodipine - therapeutic use
title Nimodipine in Acute Ischemic Stroke
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