Lactation performance of sows fed a bulky diet during gestation and receiving growth hormone-releasing factor during lactation

Forty-eight crossbred gilts were used in an experiment with a 2 X 2 X 2 factorial arrangement of treatments. Treatments were control or bulky diet during gestation (4.1 vs 15.3% crude fiber), number of meals served daily in lactation (2 vs 4), and three daily s.c. injections of saline or of 1 mg of a human growth hormone-releasing factor analog (GRF-AN) from d 3 to 29 of lactation. Weights of pigs were recorded weekly until weaning on d 33. On d 29 of lactation, milk yield was estimated and a milk sample was obtained the next day. Jugular blood samples were collected from the sows on d 3 and 28 of lactation. Feed and water intake of sows were recorded throughout the study. Feeding the bulky diet decreased water intake in gestation (P 0.001) and increased feed intake in lactation (P 0.03). The number of meals served daily had no effect on feed intake during lactation (P 0.1). Injections of GRF-AN increased IGF-I concentrations in blood (P 0.01) and in milk (P 0.001) and decreased backfat thickness (P 0.001) and feed intake (P 0.001) of sows during lactation. Pigs from sows injected with GRF-AN weighed more on d 14 (P 0.05) and had a tendency to weigh more on d 7 (P