Pharmacokinetics of sodium amoxicillin in horses

Pharmacokinetics of sodium amoxicillin in horses

The pharmacokinetics of sodium amoxicillin were investigated after intravenous and intramuscular administration of a single dose of 15 mg kg−1 bodyweight to five horses. A rapid distribution phase was noted after intravenous administration (t½α about 20 minutes). The t½β values obtained after the in...

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Veröffentlicht in:Research in veterinary science 1988-03, Vol.44 (2), p.233-236
Hauptverfasser: MONTESISSA, C., CARLI, S., SONZOGNI, O., GARLAPPI, R., SERICOLA, A.
Format: Artikel
Sprache:eng
Schlagworte:
Amoxicillin
Amoxicillin - administration & dosage
Amoxicillin - pharmacokinetics
Animals
Antibiotics
Bioavailability
Biological Availability
Horses
Horses - metabolism
Injections, Intramuscular
Injections, Intravenous - veterinary
Intravenous administration
Male
Penicillin
Pharmacokinetics
Pharmacology
Proteins
Sodium
Veterinary medicine
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Zusammenfassung:The pharmacokinetics of sodium amoxicillin were investigated after intravenous and intramuscular administration of a single dose of 15 mg kg−1 bodyweight to five horses. A rapid distribution phase was noted after intravenous administration (t½α about 20 minutes). The t½β values obtained after the intravenous and the intramuscular administration were significantly different (P
ISSN:0034-5288
1532-2661
DOI:10.1016/S0034-5288(18)30846-4