Redefining the minimal antigen-binding fragment

Redefining the minimal antigen-binding fragment

The X-ray structures of a lysozyme-complexed camel VH domain and an antigen-free llama VH domain reveal novel features that open up new possibilities for generating and engineering minimal antigen recognition units.

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Bibliographische Detailangaben
Veröffentlicht in:Nature Structural Biology 1996-09, Vol.3 (9), p.733-736
Hauptverfasser: Sheriff, Steven, Constantine, Keith L
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Binding Sites, Antibody
Biochemistry
Biological Microscopy
Camelids, New World
Camelus
Crystallography, X-Ray
Immunoglobulin Heavy Chains - chemistry
Immunoglobulin Variable Region - chemistry
Life Sciences
Membrane Biology
Models, Molecular
news-and-views
Protein Conformation
Protein Structure
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Beschreibung
Zusammenfassung:The X-ray structures of a lysozyme-complexed camel VH domain and an antigen-free llama VH domain reveal novel features that open up new possibilities for generating and engineering minimal antigen recognition units.
ISSN:1072-8368
1545-9993
2331-365X
1545-9985
DOI:10.1038/nsb0996-733