Autoantibodies against MDA-LDL in subjects with severe and minor atherosclerosis and healthy population controls

Autoantibodies against MDA-LDL in subjects with severe and minor atherosclerosis and healthy population controls

Autoantibodies against oxidized low-density lipoprotein (LDL) have been reported to be associated with atherosclerosis. However, data are not consistent. We compared the titres of autoantibodies to malondialdehyde-modified LDL in three groups, a case group with angiographically documented severe cor...

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Veröffentlicht in:Atherosclerosis 1996-05, Vol.122 (2), p.245-253
Hauptverfasser: van de Vijver, Lucy P.L., Steyger, Roland, van Poppel, Geert, Boer, Jolanda M.A., Kruijssen, Dick A.C.M., Seidell, Jacob C., Princen, Hans M.G.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Aged
Atherosclerosis
Atherosclerosis (general aspects, experimental research)
Autoantibodies
Autoantibodies - analysis
Biological and medical sciences
Blood and lymphatic vessels
Body Mass Index
Cardiology. Vascular system
Cardiovascular diseases
Case-Control Studies
Coronary Angiography
Coronary Artery Disease - blood
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - immunology
Enzyme-Linked Immunosorbent Assay
Female
Humans
LDL oxidation
Lipoproteins, LDL - drug effects
Lipoproteins, LDL - immunology
Male
Malondialdehyde - immunology
Medical sciences
Middle Aged
Oxidation-Reduction
Random Allocation
Regression Analysis
Risk Factors
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Zusammenfassung:Autoantibodies against oxidized low-density lipoprotein (LDL) have been reported to be associated with atherosclerosis. However, data are not consistent. We compared the titres of autoantibodies to malondialdehyde-modified LDL in three groups, a case group with angiographically documented severe coronary stenosis (>80% stenosis in at least 1 vessel, n = 47), a hospital control group with minor stenosis on the coronary angiography (
ISSN:0021-9150
1879-1484
DOI:10.1016/0021-9150(95)05759-5