Expression and role of epidermal growth factor receptors during differentiation of cementoblasts, osteoblasts, and periodontal ligament fibroblasts in the rat

The focus of this paper is on the formation of the initial layer of acellular extrinsic fiber cementum (AEFC) by cells originating in the dental follicle proper during root formation and on the role of epidermal growth factor (EGF) and its receptor (EGF-R) in maintaining the fibroblast phenotype in...

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Veröffentlicht in:	The Anatomical record 1996-06, Vol.245 (2), p.342-360
Hauptverfasser:	Cho, Moon‐Il, Garant, Philias R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - metabolism Animals cell differentiation Cell Differentiation - drug effects Cells, Cultured cementoblasts cementum Dental Cementum - cytology Dexamethasone - pharmacology Down-Regulation Epidermal Growth Factor - pharmacology epidermal growth factor‐receptor Fibroblasts - cytology Fibroblasts - drug effects osteoblasts Osteoblasts - cytology PDL fibroblasts periodontal ligament Periodontal Ligament - cytology Periodontal Ligament - drug effects Rats Receptor, Epidermal Growth Factor - drug effects Receptor, Epidermal Growth Factor - physiology Tooth Root - physiology
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Beschreibung
Zusammenfassung:	The focus of this paper is on the formation of the initial layer of acellular extrinsic fiber cementum (AEFC) by cells originating in the dental follicle proper during root formation and on the role of epidermal growth factor (EGF) and its receptor (EGF-R) in maintaining the fibroblast phenotype in the PDL.
ISSN:	0003-276X 1097-0185
DOI:	10.1002/(SICI)1097-0185(199606)245:2<342::AID-AR16>3.0.CO;2-P