Effect of recombinant human interleukin 2 in experimental murine coccidioidomycosis

The therapeutic effect of recombinant human interleukin 2 (rH IL-2) was assessed in experimental murine coccidioidomycosis by daily IV injection for 30 days of doses ranging decimally from 2.5 × 10 1 to 2.5 × 10 5 units. The treatment with rH IL-2 had neither adverse nor salutary effects.

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Bibliographische Detailangaben
Veröffentlicht in:	Diagnostic microbiology and infectious disease 1988-02, Vol.9 (2), p.115-118
Hauptverfasser:	Hoeprich, Paul D., Merry, Joanne M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amphotericin B - pharmacology Animals Biological and medical sciences Coccidioidomycosis - therapy Experimental mycoses and models Female Infectious diseases Interleukin-2 - pharmacology Interleukin-2 - therapeutic use Liver - microbiology Lung - microbiology Medical sciences Mice Mycoses Recombinant Proteins - pharmacology Recombinant Proteins - therapeutic use Spleen - microbiology
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Beschreibung
Zusammenfassung:	The therapeutic effect of recombinant human interleukin 2 (rH IL-2) was assessed in experimental murine coccidioidomycosis by daily IV injection for 30 days of doses ranging decimally from 2.5 × 10 1 to 2.5 × 10 5 units. The treatment with rH IL-2 had neither adverse nor salutary effects.
ISSN:	0732-8893 1879-0070
DOI:	10.1016/0732-8893(88)90104-6