Expression of C-type viral particles at implantation in the marmoset monkey

Type C RNA retroviral particles have been observed budding from the plasma membrane of syncytiotrophoblast during a study of embryo unpiantation in the common marmoset (Callithrirx jacchus). These viral particles appear in profusion at the interface of syncytiotrophoblast with cytotrophoblast. They...

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Veröffentlicht in:Human reproduction (Oxford) 1988-04, Vol.3 (3), p.395-398
Hauptverfasser: Smith, Caroline A., Moore, H.D.M.
Format: Artikel
Sprache:eng
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Zusammenfassung:Type C RNA retroviral particles have been observed budding from the plasma membrane of syncytiotrophoblast during a study of embryo unpiantation in the common marmoset (Callithrirx jacchus). These viral particles appear in profusion at the interface of syncytiotrophoblast with cytotrophoblast. They appear to be a non-infective, endogenous viral component of the host genome, although the precise role of the C-type virus in this context is unclear at present. Such viral particles have been reported previously from studies of human term placenta; however, this is the first report indicating that expression of viral particles occurs at the earliest stages of embryo implantation.
ISSN:0268-1161
1460-2350
DOI:10.1093/oxfordjournals.humrep.a136714