Direct detection of Hb C (B6 Glu‐Lys) by BseRI analysis

Hemoglobin C (B6 Glu‐Lys) can be identified by different techniques. Here we describe a restriction enzyme digestion protocol (BseRI GAGGAG N10) for direct detection of this variant. © 1996 Wiley‐Liss, Inc.

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Bibliographische Detailangaben
Veröffentlicht in:	American journal of hematology 1996-08, Vol.52 (4), p.325-326
Hauptverfasser:	Akar, N., Akar, E., Taştan, H., Cin, Ş.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Biological and medical sciences Deoxyribonucleases, Type II Site-Specific - metabolism DNA - chemistry DNA - metabolism Electrophoresis, Agar Gel Genetic Carrier Screening - methods Globins - genetics Hb C Hematology Hemoglobin C - analysis Hemoglobin C - genetics hemoglobinopathy Humans Investigative techniques, diagnostic techniques (general aspects) Medical sciences Molecular Sequence Data Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques restriction enzyme
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Beschreibung
Zusammenfassung:	Hemoglobin C (B6 Glu‐Lys) can be identified by different techniques. Here we describe a restriction enzyme digestion protocol (BseRI GAGGAG N10) for direct detection of this variant. © 1996 Wiley‐Liss, Inc.
ISSN:	0361-8609 1096-8652
DOI:	10.1002/(SICI)1096-8652(199608)52:4<325::AID-AJH16>3.0.CO;2-C