Complex translocation involving chromosomes #1, #9, and #22 in a patient with chronic myelogenous leukemia

A case of Philadelphia chromosome positive chronic myelogenous leukemia with a complex translocation involving chromosomes #1, #9, and #22 is described. All cells in the bone marrow showed this rearrangement, and Q-banding analysis showed the predominant karyotype to be 46,XY, t(1;9;22)(p22;q34;q11)...

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Veröffentlicht in:	Cancer genetics and cytogenetics 1988-06, Vol.32 (2), p.277-280
Hauptverfasser:	Adhvaryu, Siddharth G., Vyas, Rohini C., Jani, Kalyani H., Balar, Damodar B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Chromosome Banding Chromosomes, Human, Pair 1 Chromosomes, Human, Pair 22 Chromosomes, Human, Pair 9 Genetic Markers Hematologic and hematopoietic diseases Humans Karyotyping Leukemia, Myeloid - genetics Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Male Medical sciences Translocation, Genetic
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Beschreibung
Zusammenfassung:	A case of Philadelphia chromosome positive chronic myelogenous leukemia with a complex translocation involving chromosomes #1, #9, and #22 is described. All cells in the bone marrow showed this rearrangement, and Q-banding analysis showed the predominant karyotype to be 46,XY, t(1;9;22)(p22;q34;q11).
ISSN:	0165-4608 1873-4456
DOI:	10.1016/0165-4608(88)90291-9