The preparation of cultured rabies virus and the production of antiserum for human use

In this paper we describe a methodology for the preparation of the Pasteur strain of fixed rabies virus in BHK-21 clone 13 cells and also its use for the production of antisera in horses. The methodology showed here is simple, rapid, facilitates the attainment of high protective titers, and the anti...

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Veröffentlicht in:	Journal of biological standardization 1988, Vol.16 (1), p.27-32
Hauptverfasser:	Consales, C.A., Valentini, E.J.G., Albas, A., Mendonca, R.M.Z., Fuches, R.M.M., Soares, M.A., Pereira, C.A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antiserum Biological and medical sciences culture techniques Fundamental and applied biological sciences. Psychology horses Horses - immunology Immune Sera - isolation & purification Microbiology rabies Rabies virus - growth & development Rabies virus - immunology serum Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies Virology Virus Cultivation - methods zoonoses
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Beschreibung
Zusammenfassung:	In this paper we describe a methodology for the preparation of the Pasteur strain of fixed rabies virus in BHK-21 clone 13 cells and also its use for the production of antisera in horses. The methodology showed here is simple, rapid, facilitates the attainment of high protective titers, and the antisera produced are of high quality.
ISSN:	0092-1157
DOI:	10.1016/0092-1157(88)90026-1