Accurate quantification of in vivo 31P NMR signals using the variable projection method and prior knowledge

Accurate quantification of in vivo 31P NMR signals using the variable projection method and prior knowledge

Free induction decay signals are analyzed by fitting a model function directly in the time domain. No starting values are needed for linear model parameters, and omission of corrupted data points poses no problems. A significant gain of accuracy is achieved by imposing prior knowledge about the mode...

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Veröffentlicht in:Magnetic resonance in medicine 1988-01, Vol.6 (1), p.92-98
Hauptverfasser: van der Veen, J. W. C., de Beer, R., Luyten, P. R., van Ormondt, D.
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Humans
In Vitro Techniques
Investigative techniques, diagnostic techniques (general aspects)
Magnetic Resonance Spectroscopy - methods
Medical sciences
Miscellaneous. Technology
Models, Theoretical
Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques
Phosphorus
Time Factors
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Beschreibung
Zusammenfassung:Free induction decay signals are analyzed by fitting a model function directly in the time domain. No starting values are needed for linear model parameters, and omission of corrupted data points poses no problems. A significant gain of accuracy is achieved by imposing prior knowledge about the model parameters. © 1988 Academic Press, Inc.
ISSN:0740-3194
1522-2594
DOI:10.1002/mrm.1910060111