Molecular Structure of Terrecyclodiol:  A Derivative of the Antifungal Metabolite Terrecyclic Acid A from Aspergillus terreus

A strain of Aspergillus terreus, which was isolated from organic mulch and inhibited the growth of the plant pathogen Phytophthora cinnamomi, produces an antifungal metabolite when grown in liquid culture. This metabolite was isolated by bioassay-guided fractionation and identified as terrecyclic ac...

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Veröffentlicht in:Journal of natural products (Washington, D.C.) D.C.), 1996-01, Vol.59 (1), p.59-61
Hauptverfasser: Almassi, Faramak, Ghisalberti, Emilio L, Skelton, Brian W, White, Allan H
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Sprache:eng
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Zusammenfassung:A strain of Aspergillus terreus, which was isolated from organic mulch and inhibited the growth of the plant pathogen Phytophthora cinnamomi, produces an antifungal metabolite when grown in liquid culture. This metabolite was isolated by bioassay-guided fractionation and identified as terrecyclic acid A (1). X-ray diffraction studies and spectroscopic details of the derived terrecyclodiol (2) are described.
ISSN:0163-3864
1520-6025
DOI:10.1021/np960008f