How T Cells Count

The surfaces of antigen-presenting cells of the body offer many foreign peptides for the sampling and possible activation of the T cell population. How T cells know when an interaction should result in an activation to mount an immunological defense is discussed.

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Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 1996-07, Vol.273 (5271), p.78-79
1. Verfasser:	Rothenberg, Ellen V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigen presenting cells Antigen-Presenting Cells - immunology Antigens Antigens - immunology Biological and medical sciences CD28 Antigens - immunology Cellular biology Dose response relationship Down-Regulation Feedback (Response) Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immune response Immunobiology Ligands Lymphocyte Activation Lymphoid cells: ontogeny, maturation, markers, receptors, circulation and recirculation Molecules Perspectives Receptors Receptors, Antigen, T-Cell - immunology T cell antigen receptors T cells T lymphocytes T-Lymphocytes - immunology Violas
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Beschreibung
Zusammenfassung:	The surfaces of antigen-presenting cells of the body offer many foreign peptides for the sampling and possible activation of the T cell population. How T cells know when an interaction should result in an activation to mount an immunological defense is discussed.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.273.5271.78