Response to total body irradiation in dermatomyositis

Response to total body irradiation in dermatomyositis

There were two patients with severe dermatomyositis refractory to immunosuppressive therapy treated with 150 rad of total body irradiation given over a period of 5 weeks. Both patients responded promptly with minimal side‐effects and remain in partial remission 42 and 18 months after completion of t...

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Veröffentlicht in:Muscle & nerve 1988-02, Vol.11 (2), p.120-123
Hauptverfasser: Kelly, John J., Madoc-Jones, Hywel, Adelman, Lester S., Andres, Patricia L., Munsat, Theodore L.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Biological and medical sciences
Dermatomyositis - radiotherapy
Female
Humans
Male
Medical sciences
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
Whole-Body Irradiation
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Beschreibung
Zusammenfassung:There were two patients with severe dermatomyositis refractory to immunosuppressive therapy treated with 150 rad of total body irradiation given over a period of 5 weeks. Both patients responded promptly with minimal side‐effects and remain in partial remission 42 and 18 months after completion of the treatment. Total body irradiation is effective in some patients with dermatomyositis who are refractory to standard therapy.
ISSN:0148-639X
1097-4598
DOI:10.1002/mus.880110206