Localization of the spherocytosis gene to chromosome segment 8p11.22----8p21

Localization of the spherocytosis gene to chromosome segment 8p11.22----8p21

A case of hereditary spherocytosis (HS) is reported. Cytogenetic study revealed a de novo minute deletion of chromosome 8. The critical portion which affected the expression of the HS phenotype appeared to be localized to 8p11.22---8p21.1.

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Veröffentlicht in:Human genetics 1988-01, Vol.78 (1), p.94-95
Hauptverfasser: Kitatani, M, Chiyo, H, Ozaki, M, Shike, S, Miwa, S
Format: Artikel
Sprache:eng
Schlagworte:
Chromosome Banding
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 8
Humans
Infant
Karyotyping
Male
Spherocytosis, Hereditary - genetics
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Zusammenfassung:A case of hereditary spherocytosis (HS) is reported. Cytogenetic study revealed a de novo minute deletion of chromosome 8. The critical portion which affected the expression of the HS phenotype appeared to be localized to 8p11.22---8p21.1.
ISSN:0340-6717