Estrogen-secreting adrenal tumor responsive to ACTH: localization by adrenal venous sampling

In a 48-year-old man with gynecomastia but no other signs of feminization, routine evaluation revealed only minimally elevated serum estrogens. The diagnosis of an estrogen-secreting adrenal tumor was suggested by CT and confirmed by adrenal venous sampling. This tumor was found to be ACTH-responsiv...

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Veröffentlicht in:	Southern medical journal (Birmingham, Ala.) Ala.), 1988-02, Vol.81 (2), p.275-278
Hauptverfasser:	Mersey, J H, Ceballos, L, Levin, P, Busky, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Neoplasms - complications Adrenal Cortex Neoplasms - diagnosis Adrenal Cortex Neoplasms - diagnostic imaging Adrenal Cortex Neoplasms - metabolism Adrenal Glands - blood supply Adrenocorticotropic Hormone Estradiol - metabolism Estrogens - blood Estrogens - metabolism Estrone - metabolism Feminization - etiology Hemangioma - complications Hemangioma - diagnosis Hemangioma - diagnostic imaging Hemangioma - metabolism Hormones, Ectopic - blood Hormones, Ectopic - metabolism Humans Male Middle Aged Tomography, X-Ray Computed Veins
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Zusammenfassung:	In a 48-year-old man with gynecomastia but no other signs of feminization, routine evaluation revealed only minimally elevated serum estrogens. The diagnosis of an estrogen-secreting adrenal tumor was suggested by CT and confirmed by adrenal venous sampling. This tumor was found to be ACTH-responsive. Results in this patient are compared with those in normal volunteers, in whom adrenal venous sampling failed to localize estrogen secretion and in whom ACTH did not increase estrogens.
ISSN:	0038-4348
DOI:	10.1097/00007611-198802000-00034