HERPES GESTATIONIS WITH MULTIPLE RECURRENCES

Summary A case of herpes gestationis with multiple attacks is reported. These attacks occurred over five years during and after three successful pregnancies, during and after three pregnancies which resulted in miscarriages, and during menstruation. The three living children did not have any skin problems. The diagnosis was substantiated, histologically and immunohistochemically. The patient was HLA DR3 positive. She was Rhesus−ve (Rh−ve) and the two first children were Rh+ve while the third one was Rh−ve. The investigative data are discussed in relation to the possible pathogenetic factors for the diseases.