Differential Regulation of Vitamin D Receptors in Clonal Populations of a Chronic Myelogenous Leukemia Cell Line

RWLeu4 is a chronic myelogenous leukemia cell line that is sensitive to the antiproliferative and differentiation-inducing actions of 1α,25(OH)2-vitamin D3(VD3). The JMRD3cell line is a VD3-resistant variant of RWLeu4 that was selected by continuous passage of RWLeu4 in the presence of VD3. The isol...

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Veröffentlicht in:	Experimental cell research 1996-05, Vol.225 (1), p.143-150
Hauptverfasser:	Iwata, Keigo, Kouttab, Nicola, Ogata, Haruki, Morgan, John W., Maizel, Abby L., Lasky, Stephen R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Carboxylesterase Carboxylic Ester Hydrolases - metabolism Cell Differentiation Cholecalciferol - pharmacology Clone Cells DNA - metabolism Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive Lipopolysaccharide Receptors - metabolism Macrophage-1 Antigen - metabolism Molecular Sequence Data Nitroblue Tetrazolium - metabolism Oligodeoxyribonucleotides Receptors, Calcitriol - metabolism Tumor Cells, Cultured
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